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Journal: Cyborg and Bionic Systems
Article Title: Nano-Immunotherapy Synergizing Ferroptosis and STING Activation in Metastatic Bladder Cancer
doi: 10.34133/cbsystems.0458
Figure Lengend Snippet: Synergistic antitumor effect of nanomedicine induced ferroptosis and ICD. (A) Morphological changes of cells treated with nanomedicine (bright-field imaging). (B) Cell viability evaluation by Cell Counting Kit-8 (CCK-8). (C) Lipid peroxidation level and SLC7A11 gene expression regulation. (D) Correlation analysis between GSH depletion and iron death markers. (E) Quantification of cell membrane damage (LDH release). (F) ATP concentration dynamics and immunogenic death activation. (G) HMGB1 release level and DAMP signal intensity. * P < 0.05; ** P < 0.01; *** P < 0.001.
Article Snippet: The
Techniques: Imaging, Cell Counting, CCK-8 Assay, Gene Expression, Membrane, Concentration Assay, Activation Assay